Berzosertib for Dummies
-dihydroxyphenyl rings of procyanidin C1 ended up present in the construction mimicking K2E2·Pi condition. This interaction triggers the ion pathway (that's formed by residues such as among the interacting arginines, R979) to become inaccessible from your extracellular side76. This binding mode may perhaps As a result sterically impede ion Trade.